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Matrix-metalloproteinase-9 is cleaved and activated by Cathepsin K

BACKGROUND: Matrix-metalloproteinases 9 (MMP-9) belongs to the class of matrix metalloproteinases whose main function is to degrade and remodel the extracellular matrix (ECM). MMP-9 has been shown to be an integral part of many diseases where modulation of the ECM is a key step such as cancer, osteo...

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Detalles Bibliográficos
Autores principales: Christensen, Jon, Shastri, V Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518881/
https://www.ncbi.nlm.nih.gov/pubmed/26219353
http://dx.doi.org/10.1186/s13104-015-1284-8