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Global DNA methylation changes and differential gene expression in Anaplasma phagocytophilum-infected human neutrophils

BACKGROUND: Anaplasma phagocytophilum is an obligate intracellular prokaryotic pathogen that both infects and replicates within human neutrophils. The bacterium represses multiple antimicrobial functions while simultaneously increasing proinflammatory functions by reprogramming the neutrophil genome...

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Detalles Bibliográficos
Autores principales: Sinclair, Sara H. G., Yegnasubramanian, Srinivasan, Dumler, J. Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518890/
https://www.ncbi.nlm.nih.gov/pubmed/26225157
http://dx.doi.org/10.1186/s13148-015-0105-1