Crystal structure of methyl (S)-2-{(R)-4-[(tert-but­oxy­carbon­yl)amino]-3-oxo-1,2-thia­zolidin-2-yl}-3-methyl­butano­ate: a chemical model for oxidized protein tyrosine phosphatase 1B (PTP1B)

The asymmetric unit of the title compound, C(14)H(24)N(2)O(5)S, contains two independent mol­ecules (A and B). In each mol­ecule, the iso­thia­zolidin-3-one ring adopts an envelope conformation with the methyl­ene C atom as the flap. In the crystal, the A mol­ecules are linked to one another by N—H⋯...

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Detalles Bibliográficos
Autores principales: Ruddraraju, Kasi Viswanatharaju, Hillebrand, Roman, Barnes, Charles L., Gates, Kent S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518936/
https://www.ncbi.nlm.nih.gov/pubmed/26279856
http://dx.doi.org/10.1107/S2056989015010051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518936/
https://www.ncbi.nlm.nih.gov/pubmed/26279856
http://dx.doi.org/10.1107/S2056989015010051

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