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Baicalein, a Bioflavonoid, Prevents Cisplatin-Induced Acute Kidney Injury by Up-Regulating Antioxidant Defenses and Down-Regulating the MAPKs and NF-κB Pathways

Acute renal failure is a serious complication of the anticancer drug cisplatin. The potential role of baicalein, a naturally occurring bioflavonoid on cisplatin-induced renal injury is unknown. Here, we assessed the effect of baicalein against a murine model of cisplatin-induced acute renal failure...

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Detalles Bibliográficos
Autores principales: Sahu, Bidya Dhar, Kumar, Jerald Mahesh, Sistla, Ramakrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519041/
https://www.ncbi.nlm.nih.gov/pubmed/26222683
http://dx.doi.org/10.1371/journal.pone.0134139