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Interactions between αv-Integrin and HER2 and Their Role in the Invasive Phenotype of Breast Cancer Cells In Vitro and in Rat Brain

BACKGROUND: We tested the hypothesis that αv-integrin and the human epidermal growth factor receptor type 2 (HER2) interact with each other in brain trophic metastatic breast cancer cells and influence their invasive phenotype. METHODS: Clones of MDA-MB231BR human breast cancer cells with stable kno...

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Detalles Bibliográficos
Autores principales: Lal, Sangeet, Kersch, Cymon, Beeson, Kathleen A., Wu, Y. Jeffrey, Muldoon, Leslie L., Neuwelt, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519046/
https://www.ncbi.nlm.nih.gov/pubmed/26222911
http://dx.doi.org/10.1371/journal.pone.0131842