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CDK8-Cyclin C Mediates Nutritional Regulation of Developmental Transitions through the Ecdysone Receptor in Drosophila

The steroid hormone ecdysone and its receptor (EcR) play critical roles in orchestrating developmental transitions in arthropods. However, the mechanism by which EcR integrates nutritional and developmental cues to correctly activate transcription remains poorly understood. Here, we show that EcR-de...

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Detalles Bibliográficos
Autores principales: Xie, Xiao-Jun, Hsu, Fu-Ning, Gao, Xinsheng, Xu, Wu, Ni, Jian-Quan, Xing, Yue, Huang, Liying, Hsiao, Hao-Ching, Zheng, Haiyan, Wang, Chenguang, Zheng, Yani, Xiaoli, Alus M., Yang, Fajun, Bondos, Sarah E., Ji, Jun-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519132/
https://www.ncbi.nlm.nih.gov/pubmed/26222308
http://dx.doi.org/10.1371/journal.pbio.1002207