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Transcriptional Analysis of MexAB-OprM Efflux Pumps System of Pseudomonas aeruginosa and Its Role in Carbapenem Resistance in a Tertiary Referral Hospital in India

Carbapenem resistance presents severe threat to the treatment of multidrug resistant Pseudomonas aeruginosa infections. The study was undertaken to investigate the role of efflux pumps in conferring meropenem resistance and effect of single dose exposure of meropenem on transcription level of mexA g...

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Detalles Bibliográficos
Autores principales: Choudhury, Debarati, Das Talukdar, Anupam, Dutta Choudhury, Manabendra, Maurya, Anand Prakash, Paul, Deepjyoti, Dhar Chanda, Debadatta, Chakravorty, Atanu, Bhattacharjee, Amitabha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519154/
https://www.ncbi.nlm.nih.gov/pubmed/26221722
http://dx.doi.org/10.1371/journal.pone.0133842