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Genome Wide Association Study for Predictors of Progression Free Survival in Patients on Capecitabine, Oxaliplatin, Bevacizumab and Cetuximab in First-Line Therapy of Metastatic Colorectal Cancer

PURPOSE: Despite expanding options for systemic treatment, survival for metastatic colorectal cancer (mCRC) remains limited and individual response is difficult to predict. In search of pre-treatment predictors, pharmacogenetic research has mainly used a candidate gene approach. Genome wide associat...

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Detalles Bibliográficos
Autores principales: Pander, Jan, van Huis-Tanja, Lieke, Böhringer, Stefan, van der Straaten, Tahar, Gelderblom, Hans, Punt, Cornelis, Guchelaar, Henk-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519298/
https://www.ncbi.nlm.nih.gov/pubmed/26222057
http://dx.doi.org/10.1371/journal.pone.0131091