An Internally Translated MAVS Variant Exposes Its Amino-terminal TRAF-Binding Motifs to Deregulate Interferon Induction

Activation of pattern recognition receptors and proper regulation of downstream signaling are crucial for host innate immune response. Upon infection, the NF-κB and interferon regulatory factors (IRF) are often simultaneously activated to defeat invading pathogens. Mechanisms concerning differential...

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Detalles Bibliográficos
Autores principales: Minassian, Arlet, Zhang, Junjie, He, Shanping, Zhao, Jun, Zandi, Ebrahim, Saito, Takeshi, Liang, Chengyu, Feng, Pinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519330/
https://www.ncbi.nlm.nih.gov/pubmed/26221961
http://dx.doi.org/10.1371/journal.ppat.1005060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519330/
https://www.ncbi.nlm.nih.gov/pubmed/26221961
http://dx.doi.org/10.1371/journal.ppat.1005060

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