Ghrelin's Effects on Proinflammatory Cytokine Mediated Apoptosis and Their Impact on β-Cell Functionality

Ghrelin is a peptidic hormone, which stimulates cell proliferation and inhibits apoptosis in several tissues, including pancreas. In preclinical stage of type 1 diabetes, proinflammatory cytokines generate a destructive environment for β-cells known as insulitis, which results in loss of β-cell mass...

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Detalles Bibliográficos
Autores principales: Diaz-Ganete, Antonia, Baena-Nieto, Gloria, Lomas-Romero, Isabel M., Lopez-Acosta, Jose Francisco, Cozar-Castellano, Irene, Medina, Francisco, Segundo, Carmen, Lechuga-Sancho, Alfonso M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519548/
https://www.ncbi.nlm.nih.gov/pubmed/26257781
http://dx.doi.org/10.1155/2015/235727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519548/
https://www.ncbi.nlm.nih.gov/pubmed/26257781
http://dx.doi.org/10.1155/2015/235727

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