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The Role of PKC-θ in CD4+ T Cells and HIV Infection: To the Nucleus and Back Again

Protein kinase C (PKC)-θ is the only member of the PKC family that has the ability to translocate to the immunological synapse between T cells and antigen-presenting cells upon T cell receptor and MHC-II recognition. PKC-θ interacts functionally and physically with other downstream effector molecule...

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Detalles Bibliográficos
Autores principales: Phetsouphanh, Chansavath, Kelleher, Anthony D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519685/
https://www.ncbi.nlm.nih.gov/pubmed/26284074
http://dx.doi.org/10.3389/fimmu.2015.00391