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The Role of PKC-θ in CD4+ T Cells and HIV Infection: To the Nucleus and Back Again
Protein kinase C (PKC)-θ is the only member of the PKC family that has the ability to translocate to the immunological synapse between T cells and antigen-presenting cells upon T cell receptor and MHC-II recognition. PKC-θ interacts functionally and physically with other downstream effector molecule...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519685/ https://www.ncbi.nlm.nih.gov/pubmed/26284074 http://dx.doi.org/10.3389/fimmu.2015.00391 |