Interleukin-35 administration counteracts established murine type 1 diabetes – possible involvement of regulatory T cells

The anti-inflammatory cytokine IL-35 is produced by regulatory T (Treg) cells to suppress autoimmune and inflammatory responses. The role of IL-35 in type 1 diabetes (T1D) remains to be answered. To elucidate this, we investigated the kinetics of Treg cell response in the multiple low dose streptozo...

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Detalles Bibliográficos
Autores principales: Singh, Kailash, Kadesjö, Erik, Lindroos, Julia, Hjort, Marcus, Lundberg, Marcus, Espes, Daniel, Carlsson, Per-Ola, Sandler, Stellan, Thorvaldson, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519737/
https://www.ncbi.nlm.nih.gov/pubmed/26224624
http://dx.doi.org/10.1038/srep12633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519737/
https://www.ncbi.nlm.nih.gov/pubmed/26224624
http://dx.doi.org/10.1038/srep12633

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