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Interleukin-35 administration counteracts established murine type 1 diabetes – possible involvement of regulatory T cells
The anti-inflammatory cytokine IL-35 is produced by regulatory T (Treg) cells to suppress autoimmune and inflammatory responses. The role of IL-35 in type 1 diabetes (T1D) remains to be answered. To elucidate this, we investigated the kinetics of Treg cell response in the multiple low dose streptozo...
Autores principales: | Singh, Kailash, Kadesjö, Erik, Lindroos, Julia, Hjort, Marcus, Lundberg, Marcus, Espes, Daniel, Carlsson, Per-Ola, Sandler, Stellan, Thorvaldson, Lina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519737/ https://www.ncbi.nlm.nih.gov/pubmed/26224624 http://dx.doi.org/10.1038/srep12633 |
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