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miRNA-133 augments coelomocyte phagocytosis in bacteria-challenged Apostichopus japonicus via targeting the TLR component of IRAK-1 in vitro and in vivo

In this study, we explored the potential roles of miRNA-133 in regulating TLR pathways in the sea cucumber Apostichopus japonicus. Target screening of RNA-Seq data successfully identified interleukin-1 receptor-associated kinase (AjIRAK−1) as a putative target of miR-133. This result was further val...

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Detalles Bibliográficos
Autores principales: Lu, Meng, Zhang, Peng-Juan, Li, Cheng-Hua, Lv, Zhi-Meng, Zhang, Wei-Wei, Jin, Chun-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519775/
https://www.ncbi.nlm.nih.gov/pubmed/26223836
http://dx.doi.org/10.1038/srep12608