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miRNA-133 augments coelomocyte phagocytosis in bacteria-challenged Apostichopus japonicus via targeting the TLR component of IRAK-1 in vitro and in vivo
In this study, we explored the potential roles of miRNA-133 in regulating TLR pathways in the sea cucumber Apostichopus japonicus. Target screening of RNA-Seq data successfully identified interleukin-1 receptor-associated kinase (AjIRAK−1) as a putative target of miR-133. This result was further val...
Autores principales: | Lu, Meng, Zhang, Peng-Juan, Li, Cheng-Hua, Lv, Zhi-Meng, Zhang, Wei-Wei, Jin, Chun-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519775/ https://www.ncbi.nlm.nih.gov/pubmed/26223836 http://dx.doi.org/10.1038/srep12608 |
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