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Genome-wide construction of a series of designed segmental aneuploids in Saccharomyces cerevisiae

Segmental aneuploidy can play an important role in environmental adaptation. However, study of segmental aneuploids is severely hampered by the difficulty of creating them in a designed fashion. Here, we describe a PCR-mediated chromosome duplication (PCDup) technology that enables the generation of...

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Detalles Bibliográficos
Autores principales: Natesuntorn, Waranya, Iwami, Kotaro, Matsubara, Yuki, Sasano, Yu, Sugiyama, Minetaka, Kaneko, Yoshinobu, Harashima, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519793/
https://www.ncbi.nlm.nih.gov/pubmed/26224198
http://dx.doi.org/10.1038/srep12510