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Genome-wide construction of a series of designed segmental aneuploids in Saccharomyces cerevisiae
Segmental aneuploidy can play an important role in environmental adaptation. However, study of segmental aneuploids is severely hampered by the difficulty of creating them in a designed fashion. Here, we describe a PCR-mediated chromosome duplication (PCDup) technology that enables the generation of...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519793/ https://www.ncbi.nlm.nih.gov/pubmed/26224198 http://dx.doi.org/10.1038/srep12510 |