Brain feminization requires active repression of masculinization via DNA methylation

The developing mammalian brain is destined for a female phenotype unless exposed to gonadal hormones during a perinatal sensitive period. It has been assumed that the undifferentiated brain is masculinized by direct induction of transcription by ligand-activated nuclear steroid receptors. We found t...

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Detalles Bibliográficos
Autores principales: Nugent, Bridget M., Wright, Christopher L., Shetty, Amol C., Hodes, Georgia E., Lenz, Kathryn M., Mahurkar, Anup, Russo, Scott J., Devine, Scott E., McCarthy, Margaret M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519828/
https://www.ncbi.nlm.nih.gov/pubmed/25821913
http://dx.doi.org/10.1038/nn.3988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519828/
https://www.ncbi.nlm.nih.gov/pubmed/25821913
http://dx.doi.org/10.1038/nn.3988

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