Synthesis and Biological Evaluation of Novel Dehydroabietic Acid Derivatives Conjugated with Acyl-Thiourea Peptide Moiety as Antitumor Agents

A series of dehydroabietic acid (DHAA) acyl-thiourea derivatives were designed and synthesized as potent antitumor agents. The in vitro pharmacological screening results revealed that the target compounds exhibited potent cytotoxicity against HeLa, SK-OV-3 and MGC-803 tumor cell lines, while they sh...

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Detalles Bibliográficos
Autores principales: Jin, Le, Qu, Hong-En, Huang, Xiao-Chao, Pan, Ying-Ming, Liang, Dong, Chen, Zhen-Feng, Wang, Heng-Shan, Zhang, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519859/
https://www.ncbi.nlm.nih.gov/pubmed/26132564
http://dx.doi.org/10.3390/ijms160714571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519859/
https://www.ncbi.nlm.nih.gov/pubmed/26132564
http://dx.doi.org/10.3390/ijms160714571

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