Differences between Mice and Humans in Regulation and the Molecular Network of Collagen, Type III, Alpha-1 at the Gene Expression Level: Obstacles that Translational Research Must Overcome

Collagen, type III, alpha-1 (COL3A1) is essential for normal collagen I fibrillogenesis in many organs. There are differences in phenotypes of mutations in the COL3A1 gene in humans and mutations in mice. In order to investigate whether the regulation and gene network of COL3A1 is the same in health...

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Detalles Bibliográficos
Autores principales: Wang, Lishi, Liu, Hongchao, Jiao, Yan, Wang, Erjian, Clark, Stephen H., Postlethwaite, Arnold E., Gu, Weikuan, Chen, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519886/
https://www.ncbi.nlm.nih.gov/pubmed/26151842
http://dx.doi.org/10.3390/ijms160715031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519886/
https://www.ncbi.nlm.nih.gov/pubmed/26151842
http://dx.doi.org/10.3390/ijms160715031

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