Understanding Xeroderma Pigmentosum Complementation Groups Using Gene Expression Profiling after UV-Light Exposure

Children with the recessive genetic disorder Xeroderma Pigmentosum (XP) have extreme sensitivity to UV-light, a 10,000-fold increase in skin cancers from age 2 and rarely live beyond 30 years. There are seven genetic subgroups of XP, which are all resultant of pathogenic mutations in genes in the nu...

Descripción completa

Detalles Bibliográficos
Autores principales: Bowden, Nikola A., Beveridge, Natalie J., Ashton, Katie A., Baines, Katherine J., Scott, Rodney J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519934/
https://www.ncbi.nlm.nih.gov/pubmed/26184184
http://dx.doi.org/10.3390/ijms160715985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519934/
https://www.ncbi.nlm.nih.gov/pubmed/26184184
http://dx.doi.org/10.3390/ijms160715985

Ejemplares similares