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Legionella suppresses the host unfolded protein response via multiple mechanisms

The intracellular pathogen, Legionella pneumophila, secretes ∼300 effector proteins to modulate the host environment. Given the intimate interaction between L. pneumophila and the endoplasmic reticulum, we investigated the role of the host unfolded protein response (UPR) during L. pneumophila infect...

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Detalles Bibliográficos
Autores principales: Treacy-Abarca, Sean, Mukherjee, Shaeri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519984/
https://www.ncbi.nlm.nih.gov/pubmed/26219498
http://dx.doi.org/10.1038/ncomms8887