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Adjuvant chemotherapy with gemcitabine and cisplatin compared to observation after curative intent resection of cholangiocarcinoma and muscle invasive gallbladder carcinoma (ACTICCA-1 trial) - a randomized, multidisciplinary, multinational phase III trial

BACKGROUND: Despite complete resection, disease-free survival (DFS) of patients with cholangiocarcinoma (CCA) is less than 65 % after one year and not more than 35 % after three years. For muscle invasive gallbladder carcinoma (GBCA), prognosis is even worse, with an overall survival (OS) of only 30...

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Detalles Bibliográficos
Autores principales: Stein, Alexander, Arnold, Dirk, Bridgewater, John, Goldstein, David, Jensen, Lars Henrik, Klümpen, Heinz-Josef, Lohse, Ansgar W., Nashan, Björn, Primrose, John, Schrum, Silke, Shannon, Jenny, Vettorazzi, Eik, Wege, Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520064/
https://www.ncbi.nlm.nih.gov/pubmed/26228433
http://dx.doi.org/10.1186/s12885-015-1498-0