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Association of HLA-DRB1 amino acid residues with giant cell arteritis: genetic association study, meta-analysis and geo-epidemiological investigation

INTRODUCTION: Giant cell arteritis (GCA) is an autoimmune disease commonest in Northern Europe and Scandinavia. Previous studies report various associations with HLA-DRB1*04 and HLA-DRB1*01; HLA-DRB1 alleles show a gradient in population prevalence within Europe. Our aims were (1) to determine which...

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Detalles Bibliográficos
Autores principales: Mackie, Sarah Louise, Taylor, John C., Haroon-Rashid, Lubna, Martin, Stephen, Dasgupta, Bhaskar, Gough, Andrew, Green, Michael, Hordon, Lesley, Jarrett, Stephen, Pease, Colin T., Barrett, Jennifer H., Watts, Richard, Morgan, Ann W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520081/
https://www.ncbi.nlm.nih.gov/pubmed/26223536
http://dx.doi.org/10.1186/s13075-015-0692-4