A functional variant in the UBE2B gene promoter is associated with idiopathic azoospermia

BACKGROUND: A variety of genetic variants lead to abnormal human spermatogenesis. The ubiquitin-conjugating enzyme E2B (UBE2B) plays a significant role in spermatogenesis as Ube2b-knockout male mice are infertile. METHODS: In this study, we sequenced the exon and promoter region of UBE2B in 776 pati...

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Detalles Bibliográficos
Autores principales: Mou, Lisha, Zhang, Qiang, Diao, Ruiying, Cai, Zhiming, Gui, Yaoting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520152/
https://www.ncbi.nlm.nih.gov/pubmed/26223869
http://dx.doi.org/10.1186/s12958-015-0074-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520152/
https://www.ncbi.nlm.nih.gov/pubmed/26223869
http://dx.doi.org/10.1186/s12958-015-0074-4

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