Cargando…
Identification and characterization of a novel ISG15-ubiquitin mixed chain and its role in regulating protein homeostasis
As a ubiquitin-like modifier, ISG15 is conjugated to many cellular proteins in a process termed protein ISGylation. However, the crosstalk between protein ISGylation and the ubiquitin proteasome system is not fully understood. Here, we report that cellular ubiquitin is a substrate of ISG15 and Lys 2...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520236/ https://www.ncbi.nlm.nih.gov/pubmed/26226047 http://dx.doi.org/10.1038/srep12704 |