De-DUFing the DUFs: Deciphering distant evolutionary relationships of Domains of Unknown Function using sensitive homology detection methods

BACKGROUND: In the post-genomic era where sequences are being determined at a rapid rate, we are highly reliant on computational methods for their tentative biochemical characterization. The Pfam database currently contains 3,786 families corresponding to “Domains of Unknown Function” (DUF) or “Unch...

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Detalles Bibliográficos
Autores principales: Mudgal, Richa, Sandhya, Sankaran, Chandra, Nagasuma, Srinivasan, Narayanaswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520260/
https://www.ncbi.nlm.nih.gov/pubmed/26228684
http://dx.doi.org/10.1186/s13062-015-0069-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520260/
https://www.ncbi.nlm.nih.gov/pubmed/26228684
http://dx.doi.org/10.1186/s13062-015-0069-2

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