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Therapeutic Effect of Berberine on Huntington’s Disease Transgenic Mouse Model

Huntington disease (HD) represents a family of neurodegenerative diseases that are caused by misfolded proteins. The misfolded proteins accumulate in the affected brain regions in an age-dependent manner to cause late-onset neurodegeneration. Transgenic mouse models expressing the HD protein, huntin...

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Detalles Bibliográficos
Autores principales: Jiang, Wenxiao, Wei, Wenjie, Gaertig, Marta A., Li, Shihua, Li, Xiao-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520448/
https://www.ncbi.nlm.nih.gov/pubmed/26225560
http://dx.doi.org/10.1371/journal.pone.0134142