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Genome-Wide Analyses Suggest Mechanisms Involving Early B-Cell Development in Canine IgA Deficiency

Immunoglobulin A deficiency (IgAD) is the most common primary immune deficiency disorder in both humans and dogs, characterized by recurrent mucosal tract infections and a predisposition for allergic and other immune mediated diseases. In several dog breeds, low IgA levels have been observed at a hi...

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Detalles Bibliográficos
Autores principales: Olsson, Mia, Tengvall, Katarina, Frankowiack, Marcel, Kierczak, Marcin, Bergvall, Kerstin, Axelsson, Erik, Tintle, Linda, Marti, Eliane, Roosje, Petra, Leeb, Tosso, Hedhammar, Åke, Hammarström, Lennart, Lindblad-Toh, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520476/
https://www.ncbi.nlm.nih.gov/pubmed/26225558
http://dx.doi.org/10.1371/journal.pone.0133844