Loss of DDB1 Leads to Transcriptional p53 Pathway Activation in Proliferating Cells, Cell Cycle Deregulation, and Apoptosis in Zebrafish Embryos

DNA damage-binding protein 1 (DDB1) is a large subunit of the heterodimeric DDB complex that recognizes DNA lesions and initiates the nucleotide excision repair process. DDB1 is also a component of the CUL4 E3 ligase complex involved in a broad spectrum of cellular processes by targeted ubiquitinati...

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Detalles Bibliográficos
Autores principales: Hu, Zhilian, Holzschuh, Jochen, Driever, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520591/
https://www.ncbi.nlm.nih.gov/pubmed/26225764
http://dx.doi.org/10.1371/journal.pone.0134299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520591/
https://www.ncbi.nlm.nih.gov/pubmed/26225764
http://dx.doi.org/10.1371/journal.pone.0134299

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