Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA

Antibacterial drugs with novel scaffolds and new mechanisms of action are desperately needed to address the growing problem of antibiotic resistance. The periplasmic oxidative folding system in Gram-negative bacteria represents a possible target for anti-virulence antibacterials. By targeting virule...

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Detalles Bibliográficos
Autores principales: Duprez, Wilko, Bachu, Prabhakar, Stoermer, Martin J., Tay, Stephanie, McMahon, Róisín M., Fairlie, David P., Martin, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520593/
https://www.ncbi.nlm.nih.gov/pubmed/26225423
http://dx.doi.org/10.1371/journal.pone.0133805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520593/
https://www.ncbi.nlm.nih.gov/pubmed/26225423
http://dx.doi.org/10.1371/journal.pone.0133805

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