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Genotype and Haplotype Analyses of TP53 Gene in Breast Cancer Patients: Association with Risk and Clinical Outcomes

Variations in the TP53 gene have been suggested to play a role in many cancers, including breast. We previously observed an association between TP53 haplotypes based on four polymorphisms (rs17878362, rs1042522, rs12947788, and rs17884306) and the risk of colorectal and pancreatic cancer. Based on t...

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Detalles Bibliográficos
Autores principales: Vymetalkova, Veronika, Soucek, Pavel, Kunicka, Tereza, Jiraskova, Katerina, Brynychova, Veronika, Pardini, Barbara, Novosadova, Vendula, Polivkova, Zdena, Kubackova, Katerina, Kozevnikovova, Renata, Ambrus, Miloslav, Vodickova, Ludmila, Naccarati, Alessio, Vodicka, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520609/
https://www.ncbi.nlm.nih.gov/pubmed/26226484
http://dx.doi.org/10.1371/journal.pone.0134463