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Key role of publication of clinical data for target validation
Drug discovery productivity has failed to improve markedly in recent years and a key issue is high attrition due to efficacy failures in initial proof-of concept clinical studies. This reflects the fact that preclinical “target validation” studies do not always translate into man, where ultimate tar...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley & Sons, Ltd
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520621/ https://www.ncbi.nlm.nih.gov/pubmed/26236489 http://dx.doi.org/10.1002/prp2.163 |