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Synergistic antiproliferative effect of imatinib and adriamycin in platelet-derived growth factor receptor-expressing osteosarcoma cells

Osteosarcoma (OS) is the most frequent primary solid malignant tumor of bone. Its prognosis remains poor in the substantial proportion of patients who do not respond to chemotherapy and novel therapeutic options are therefore needed. We previously established a mouse model that mimics the aggressive...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Sayaka I, Ueki, Arisa, Sugihara, Eiji, Onishi, Nobuyuki, Yaguchi, Tomonori, Kawakami, Yutaka, Horiuchi, Keisuke, Morioka, Hideo, Matsumoto, Morio, Nakamura, Masaya, Muto, Akihiro, Toyama, Yoshiaki, Saya, Hideyuki, Shimizu, Takatsune
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520639/
https://www.ncbi.nlm.nih.gov/pubmed/25940371
http://dx.doi.org/10.1111/cas.12686