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Comprehensive transcriptomic analysis of molecularly targeted drugs in cancer for target pathway evaluation

Targeted therapy is a rational and promising strategy for the treatment of advanced cancer. For the development of clinical agents targeting oncogenic signaling pathways, it is important to define the specificity of compounds to the target molecular pathway. Genome-wide transcriptomic analysis is an...

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Detalles Bibliográficos
Autores principales: Mashima, Tetsuo, Ushijima, Masaru, Matsuura, Masaaki, Tsukahara, Satomi, Kunimasa, Kazuhiro, Furuno, Aki, Saito, Sakae, Kitamura, Masami, Soma-Nagae, Taeko, Seimiya, Hiroyuki, Dan, Shingo, Yamori, Takao, Tomida, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520644/
https://www.ncbi.nlm.nih.gov/pubmed/25911996
http://dx.doi.org/10.1111/cas.12682