Cargando…
Comprehensive transcriptomic analysis of molecularly targeted drugs in cancer for target pathway evaluation
Targeted therapy is a rational and promising strategy for the treatment of advanced cancer. For the development of clinical agents targeting oncogenic signaling pathways, it is important to define the specificity of compounds to the target molecular pathway. Genome-wide transcriptomic analysis is an...
Autores principales: | Mashima, Tetsuo, Ushijima, Masaru, Matsuura, Masaaki, Tsukahara, Satomi, Kunimasa, Kazuhiro, Furuno, Aki, Saito, Sakae, Kitamura, Masami, Soma-Nagae, Taeko, Seimiya, Hiroyuki, Dan, Shingo, Yamori, Takao, Tomida, Akihiro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520644/ https://www.ncbi.nlm.nih.gov/pubmed/25911996 http://dx.doi.org/10.1111/cas.12682 |
Ejemplares similares
-
Disrupting ATF4 Expression Mechanisms Provides an Effective Strategy for BRAF-Targeted Melanoma Therapy
por: Nagasawa, Ikuko, et al.
Publicado: (2020) -
Lamellarin 14, a derivative of marine alkaloids, inhibits the T790M/C797S mutant epidermal growth factor receptor
por: Nishiya, Naoyuki, et al.
Publicado: (2021) -
Mitochondrial deficiency impairs hypoxic induction of HIF-1 transcriptional activity and retards tumor growth
por: Koido, Masaru, et al.
Publicado: (2017) -
TBL2 Is a Novel PERK-Binding Protein that Modulates Stress-Signaling and Cell Survival during Endoplasmic Reticulum Stress
por: Tsukumo, Yoshinori, et al.
Publicado: (2014) -
Spautin-1 inhibits mitochondrial complex I and leads to suppression of the unfolded protein response and cell survival during glucose starvation
por: Kunimasa, Kazuhiro, et al.
Publicado: (2022)