MT95-4, a fully humanized antibody raised against aminopeptidase N, reduces tumor progression in a mouse model

Aminopeptidase N (APN/CD13) is involved in tumor cell invasion and tumor angiogenesis and is considered a promising therapeutic target in the treatment of cancer. To develop a novel monoclonal antibody-based cancer therapy targeting APN/CD13, we established a fully humanized anti-APN/CD13 monoclonal...

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Detalles Bibliográficos
Autores principales: Akita, Shin, Hattori, Noboru, Masuda, Takeshi, Horimasu, Yasushi, Nakashima, Taku, Iwamoto, Hiroshi, Fujitaka, Kazunori, Miyake, Masayuki, Kohno, Nobuoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520645/
https://www.ncbi.nlm.nih.gov/pubmed/25950387
http://dx.doi.org/10.1111/cas.12692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520645/
https://www.ncbi.nlm.nih.gov/pubmed/25950387
http://dx.doi.org/10.1111/cas.12692

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