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The Crosstalk between Nrf2 and TGF-β1 in the Epithelial-Mesenchymal Transition of Pancreatic Duct Epithelial Cells

Nrf2 and TGF-β1 both affect tumorigenesis in a dual fashion, either by preventing carcinogen induced carcinogenesis and suppressing tumor growth, respectively, or by conferring cytoprotection and invasiveness to tumor cells during malignant transformation. Given the involvement of Nrf2 and TGF-β1 in...

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Detalles Bibliográficos
Autores principales: Arfmann-Knübel, Sarah, Struck, Birte, Genrich, Geeske, Helm, Ole, Sipos, Bence, Sebens, Susanne, Schäfer, Heiner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520686/
https://www.ncbi.nlm.nih.gov/pubmed/26226105
http://dx.doi.org/10.1371/journal.pone.0132978