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The Crosstalk between Nrf2 and TGF-β1 in the Epithelial-Mesenchymal Transition of Pancreatic Duct Epithelial Cells
Nrf2 and TGF-β1 both affect tumorigenesis in a dual fashion, either by preventing carcinogen induced carcinogenesis and suppressing tumor growth, respectively, or by conferring cytoprotection and invasiveness to tumor cells during malignant transformation. Given the involvement of Nrf2 and TGF-β1 in...
Autores principales: | Arfmann-Knübel, Sarah, Struck, Birte, Genrich, Geeske, Helm, Ole, Sipos, Bence, Sebens, Susanne, Schäfer, Heiner |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520686/ https://www.ncbi.nlm.nih.gov/pubmed/26226105 http://dx.doi.org/10.1371/journal.pone.0132978 |
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