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Conformational Switching of a Foldamer in a Multicomponent System by pH-Filtered Selection between Competing Noncovalent Interactions

[Image: see text] Biomolecular systems are able to respond to their chemical environment through reversible, selective, noncovalent intermolecular interactions. Typically, these interactions induce conformational changes that initiate a signaling cascade, allowing the regulation of biochemical pathw...

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Detalles Bibliográficos
Autores principales: Brioche, Julien, Pike, Sarah J., Tshepelevitsh, Sofja, Leito, Ivo, Morris, Gareth A., Webb, Simon J., Clayden, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520694/
https://www.ncbi.nlm.nih.gov/pubmed/25915163
http://dx.doi.org/10.1021/jacs.5b03284