Ubiquilin 1 Promotes IFN-γ-Induced Xenophagy of Mycobacterium tuberculosis

The success of Mycobacterium tuberculosis (Mtb) as a pathogen rests upon its ability to grow intracellularly in macrophages. Interferon-gamma (IFN-γ) is critical in host defense against Mtb and stimulates macrophage clearance of Mtb through an autophagy pathway. Here we show that the host protein ub...

Descripción completa

Detalles Bibliográficos
Autores principales: Sakowski, Erik T., Koster, Stefan, Portal Celhay, Cynthia, Park, Heidi S., Shrestha, Elina, Hetzenecker, Stefanie E., Maurer, Katie, Cadwell, Ken, Philips, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520715/
https://www.ncbi.nlm.nih.gov/pubmed/26225865
http://dx.doi.org/10.1371/journal.ppat.1005076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520715/
https://www.ncbi.nlm.nih.gov/pubmed/26225865
http://dx.doi.org/10.1371/journal.ppat.1005076

Ejemplares similares