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Ubiquilin 1 Promotes IFN-γ-Induced Xenophagy of Mycobacterium tuberculosis
The success of Mycobacterium tuberculosis (Mtb) as a pathogen rests upon its ability to grow intracellularly in macrophages. Interferon-gamma (IFN-γ) is critical in host defense against Mtb and stimulates macrophage clearance of Mtb through an autophagy pathway. Here we show that the host protein ub...
Autores principales: | Sakowski, Erik T., Koster, Stefan, Portal Celhay, Cynthia, Park, Heidi S., Shrestha, Elina, Hetzenecker, Stefanie E., Maurer, Katie, Cadwell, Ken, Philips, Jennifer A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520715/ https://www.ncbi.nlm.nih.gov/pubmed/26225865 http://dx.doi.org/10.1371/journal.ppat.1005076 |
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