Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes

Expression of the intermediate filament protein keratin 17 (K17) is robustly upregulated in inflammatory skin diseases and in many tumors originating in stratified and pseudostratified epithelia(1-3). We report that Autoimmune regulator (Aire), a transcriptional regulator, is inducibly expressed in...

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Detalles Bibliográficos
Autores principales: Hobbs, Ryan P., DePianto, Daryle J., Jacob, Justin T., Han, Minerva C., Chung, Byung-Min, Batazzi, Adriana S., Poll, Brian G., Guo, Yajuan, Han, Jingnan, Ong, SuFey, Zheng, Wenxin, Taube, Janis M., Čiháková, Daniela, Wan, Fengyi, Coulombe, Pierre A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520766/
https://www.ncbi.nlm.nih.gov/pubmed/26168014
http://dx.doi.org/10.1038/ng.3355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520766/
https://www.ncbi.nlm.nih.gov/pubmed/26168014
http://dx.doi.org/10.1038/ng.3355

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