Hyperinsulinemia Enhances Hepatic Expression of the Fatty Acid Transporter Cd36 and Provokes Hepatosteatosis and Hepatic Insulin Resistance

Hepatosteatosis is associated with the development of both hepatic insulin resistance and Type 2 diabetes. Hepatic expression of Cd36, a fatty acid transporter, is enhanced in obese and diabetic murine models and human nonalcoholic fatty liver disease, and thus it correlates with hyperinsulinemia, s...

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Detalles Bibliográficos
Autores principales: Steneberg, Pär, Sykaras, Alexandros G., Backlund, Fredrik, Straseviciene, Jurate, Söderström, Ingegerd, Edlund, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521028/
https://www.ncbi.nlm.nih.gov/pubmed/26085100
http://dx.doi.org/10.1074/jbc.M115.640292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521028/
https://www.ncbi.nlm.nih.gov/pubmed/26085100
http://dx.doi.org/10.1074/jbc.M115.640292

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