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Ca(2+) Channel Re-localization to Plasma-Membrane Microdomains Strengthens Activation of Ca(2+)-Dependent Nuclear Gene Expression

In polarized cells or cells with complex geometry, clustering of plasma-membrane (PM) ion channels is an effective mechanism for eliciting spatially restricted signals. However, channel clustering is also seen in cells with relatively simple topology, suggesting it fulfills a more fundamental role i...

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Detalles Bibliográficos
Autores principales: Samanta, Krishna, Kar, Pulak, Mirams, Gary R., Parekh, Anant B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521080/
https://www.ncbi.nlm.nih.gov/pubmed/26146085
http://dx.doi.org/10.1016/j.celrep.2015.06.018