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Ca(2+) Channel Re-localization to Plasma-Membrane Microdomains Strengthens Activation of Ca(2+)-Dependent Nuclear Gene Expression
In polarized cells or cells with complex geometry, clustering of plasma-membrane (PM) ion channels is an effective mechanism for eliciting spatially restricted signals. However, channel clustering is also seen in cells with relatively simple topology, suggesting it fulfills a more fundamental role i...
Autores principales: | Samanta, Krishna, Kar, Pulak, Mirams, Gary R., Parekh, Anant B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521080/ https://www.ncbi.nlm.nih.gov/pubmed/26146085 http://dx.doi.org/10.1016/j.celrep.2015.06.018 |
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