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Combined transcriptome studies identify AFF3 as a mediator of the oncogenic effects of β-catenin in adrenocortical carcinoma

Adrenocortical cancer (ACC) is a very aggressive tumor, and genomics studies demonstrate that the most frequent alterations of driver genes in these cancers activate the Wnt/β-catenin signaling pathway. However, the adrenal-specific targets of oncogenic β-catenin-mediating tumorigenesis have not bei...

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Detalles Bibliográficos
Autores principales: Lefèvre, L, Omeiri, H, Drougat, L, Hantel, C, Giraud, M, Val, P, Rodriguez, S, Perlemoine, K, Blugeon, C, Beuschlein, F, de Reyniès, A, Rizk-Rabin, M, Bertherat, J, Ragazzon, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521181/
https://www.ncbi.nlm.nih.gov/pubmed/26214578
http://dx.doi.org/10.1038/oncsis.2015.20