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Acetaminophen-induced Liver Injury: from Animal Models to Humans

Drug-induced liver injury is an important clinical problem and a challenge for drug development. Whereas progress in understanding rare and unpredictable (idiosyncratic) drug hepatotoxicity is severely hampered by the lack of relevant animal models, enormous insight has been gained in the area of pr...

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Detalles Bibliográficos
Autores principales: Jaeschke, Hartmut, Xie, Yuchao, McGill, Mitchell R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521247/
https://www.ncbi.nlm.nih.gov/pubmed/26355817
http://dx.doi.org/10.14218/JCTH.2014.00014