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Stem Cell Strategies to Evaluate Idiosyncratic Drug-induced Liver Injury

The host-dependent nature of idiosyncratic drug-induced liver injury (iDILI) suggests that rare genetic polymorphisms may contribute to the disease. Indeed, a few mutations in key genes have already been identified using conventional human genetics approaches. Over 50 commonly used drugs can precipi...

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Detalles Bibliográficos
Autores principales: Krueger, Winfried, Boelsterli, Urs A., Rasmussen, Theodore P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521249/
https://www.ncbi.nlm.nih.gov/pubmed/26355943
http://dx.doi.org/10.14218/JCTH.2014.00012