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Autophagic digestion of Leishmania major by host macrophages is associated with differential expression of BNIP3, CTSE, and the miRNAs miR-101c, miR-129, and miR-210

BACKGROUND: Autophagy participates in innate immunity by eliminating intracellular pathogens. Consequently, numerous microorganisms have developed strategies to impair the autophagic machinery in phagocytes. In the current study, interactions between Leishmania major (L. m.) and the autophagic machi...

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Detalles Bibliográficos
Autores principales: Frank, Benjamin, Marcu, Ana, de Oliveira Almeida Petersen, Antonio Luis, Weber, Heike, Stigloher, Christian, Mottram, Jeremy C., Scholz, Claus Juergen, Schurigt, Uta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521392/
https://www.ncbi.nlm.nih.gov/pubmed/26226952
http://dx.doi.org/10.1186/s13071-015-0974-3