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Brca1 is expressed in human microglia and is dysregulated in human and animal model of ALS

BACKGROUND: There is growing evidence that microglia are key players in the pathological process of amyotrophic lateral sclerosis (ALS). It is suggested that microglia have a dual role in motoneurone degeneration through the release of both neuroprotective and neurotoxic factors. RESULTS: To identif...

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Detalles Bibliográficos
Autores principales: Noristani, Harun Najib, Sabourin, Jean Charles, Gerber, Yannick Nicolas, Teigell, Marisa, Sommacal, Andreas, dM Vivanco, Maria, Weber, Markus, Perrin, Florence Evelyne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521418/
https://www.ncbi.nlm.nih.gov/pubmed/26227626
http://dx.doi.org/10.1186/s13024-015-0023-x